Genetic and lifestyle risk factors for MRI-defined brain infarcts in a population-based setting

- Chauhan, Ganesh, Adams, Hieab H. H., Satizabal, Claudia L., Bis, Joshua C., Teumer, Alexander, Sargurupremraj, Muralidharan, Hofer, Edith, Trompet, Stella, Hilal, Saima, Smith, Albert Vernon, Jian, Xueqiu, Malik, Rainer, Traylor, Matthew, Pulit, Sara L., Amouyel, Philippe, Mazoyer, Bernard, Zhu, Yi-Cheung, Kaffashian, Sara, Schilling, Sabrina, Beecham, Gary W., Montine, Thomas J., Schellenberg, G. D., Kjartansson, O., Guðnason, V., Knopman, D. S., Griswold, M. E., Windham, B. G., Gottesman, R. F., Mosley, T. H., Schmidt, R., Saba, Y., Schmidt, H., Takeuchi, F., Yamaguchi, S., Nabika, T., Kato, N, Rajan, K. B., Aggarwal, N. T., De Jager, P. L., Evans, D. A., Psaty, B M., Rotter, J. I., Rice, K., Lopez, O. L., Liao, J., Chen, C., Cheng, C.Y., Wong, T. Y., Ikram, M. K., van der Lee, S. J., Amin, N., Chouraki, V., Destefano, A. L., Aparicio, H. J., Romero, J. R., Maillard, P., Decarli, C., Wardlaw, J. M., Del C. Valdés Hernández, M., Luciano, M., Liewald, D., Deary, I. J., Starr, J. M., Bastin, M. E., Maniega, S. M., Slagboom, P. E., Beekman, M., Deelen, J., Uh, H. W., Lemmens, R., Brodaty, H., Wright, MJ., Ames, D., Boncoraglio, G. B., Hopewell, J. C., Beecham, A. H., Blanton, S. H., Wright, C. B., Sacco, R. L., Wen, W., Thalamuthu, A., Armstrong, N. J., Chong, E., Schofield, P. R., Kwok, J. B., van der Grond, J., Stott, D. J., Ford, I., Jukema, J. W., Vernooij, M. W., Hofman, A., Uitterlinden, A. G., van der Lugt, A., Wittfeld, K., Grabe, H. J., Hosten, N., von Sarnowski, B., Völker, U., Levi, Christopher, Jimenez-Conde, J., Sharma, P., Sudlow, C. L. M., Rosand, J., Woo, D., Cole, J. W., Mechia, J. F., Slowik, A., Thijs, V., Lindgren, A., Melander, O., Grewal, R. P., Rundek, T., Rexrode, K., Arnett, D. K., Jern, C., Johnson, J. A., Benavente, O. R., Asselbergs, F. R., Srikanth, V., Thomson, R., McWhirter, R., Moran, C., Callisaya, M., Phan, T., Rutten-Jacobs, L. C. A., Bevan, S., Tzourio, C., Mather, K. A., Sachdev, P. S., van Duijn, C. M., Worrall, B. B., Dichgans, M., Kittner, S. J., Markus, H. S., Ikram, M. A., Fornage, M., Launer, L. J., Seshadri, S., Longstreth, W. T., Debette, S.

Analysis of shared heritability in common disorders of the brain

- Anttila, Verneri, Bulik-Sullivan, Brendan, Patsopoulos, Nikolaos A., Ripke, Stephan, Wei, Zhi, Yu, Dongmei, Lee, Phil H., Turley, Patrick, Grenier-Boley, Benjamin, Chouraki, Vincent, Kamatani, Yoichiro, Berr, Claudine, Finucane, Hilary K., Holliday, Elizabeth, Attia, John, Cairns, Murray, Loughland, Carmel, Schall, Ulrich, Henskens, Frans, Scott, Rodney, Reitz, C, Goate, AM, Huentelman, MJ, Walters, Raymond K., Ilyas Kamboh, M, Larson, EB, Rogaeva, E, George-Hyslop, PS, Hakonarson, H, Kukull, WA, Farrer, LA, Barnes, LL, Beach, TG, Yesim Demirci, F, Bras, Jose, Head, E, Hulette, CM, Jicha, GA, Kauwe, JSK, Kaye, JA, Leverenz, JB, Levey, AI, Lieberman, AP, Pankratz, VS, Poon, WW, Duncan, Laramie, Quinn, JF, Saykin, AJ, Schneider, LS, Smith, AG, Escott-Price, Valentina, Falcone, Guido J., Gormley, Padhraig, Malik, Rainer

Genetics of the thrombomodulin-endothelial cell protein C receptor system and the risk of early-onset ischemic stroke

- Cole, John W., Xu, Huichun, Ryan, Kathleen, Jaworek, Thomas, Dueker, Nicole, McArdle, Patrick, Gaynor, Brady, Cheng, Yu-Ching, O'Connell, Jeffrey, Bevan, Steve, Malik, Rainer, Ahmed, Naveed Uddin, Amouyel, Philippe, Anjum, Sheraz, Bis, Joshua C., Crosslin, David, Danesh, John, Engelter, Stefan T., Fornage, Myriam, Frossard, Philippe, Holliday, Elizabeth, Levi, Christopher

Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes

- Malik, Rainer, Chauhan, Ganesh, Anderson, Christopher D., Chong, Michael, Adams, Hieab H. H., Ago, Tetsuro, Almgren, Peter, Amouyel, Philippe, Ay, Hakan, Bartz, Traci M., Benavente, Oscar R., Bevan, Steve, Traylor, Matthew, Holliday, Elizabeth G., Attia, John, Levi, Christopher R., Carrera, C, Carty, CL, Chasman, DI, Chen, W-M, Cole, JW, Correa, A, Cotlarciuc, I, Sargurupremraj, Muralidharan, Cruchaga, C, Danesh, J, de Bakker, PIW, DeStefano, AL, Den Hoed, M, Duan, Q, Engelter, ST, Falcone, GJ, Gottesman, RF, Grewal, RP, Okada, Yukinori, Gudnason, V, Gustafsson, S, Haessler, J, Harris, TB, Hassan, A, Havulinna, AS, Heckbert, SR, Holliday, EG, Howard, G, Hsu, F-C, Mishra, Aniket, Hyacinth, HI, Ikram, MA, Ingelsson, E, Irvin, MR, Jian, X, Jiménez-Conde, J, Johnson, JA, Jukema, JW, Kanai, M, Keene, KL, Rutten-Jacobs, Loes, Kissela, BM, Kleindorfer, DO, Kooperberg, C, Kubo, M, Lange, LA, Langefeld, CD, Langenberg, C, Launer, LJ, Lee, J-M, Lemmens, R, Giese, Anne-Katrin, van der Laan, Sander W., Gretarsdottir, Solveig

Common coding variant in SERPINA1 increases the risk for large artery stroke

- Malik, Rainer, Cardenas, IF, Rothwell, PM, Levi, C, Attia, J, Sudlow, CLM, Braun, D, Markus, HS, Wintrode, PL, Berger, K, Jenne, DE, Dichgans, M, Dau, Therese, Seixas, Susana, Bevan, Steve, Lincz, Lisa F., Holliday, Elizabeth G., Burgess, Annette I., Rannikmäe, Kristiina, Minnerup, Jens, Kriebel, Jennifer, Waldenberger, Melanie, Müller-Nurasyid, Martina, Gonik, Maria, Levi, Christopher, Attia, John, Maguire, Jane, Sivakumar, Anirudh, Deredge, Daniel J., Edeleva, Evgeniia V., Götzfried, Jessica, van der Laan, Sander W., Pasterkamp, Gerard, Beaufort, Nathalie

Genetic variation at 16q24.2 is associated with small vessel stroke

- Traylor, Matthew, Malik, Rainer, Yet, Idil, Spector, Tim D., Bell, Jordana T., Hannon, Ellis, Mill, Jonathan, Chauhan, Ganesh, Debette, Stephanie, Bis, Joshua C., Longstreth, W. T., Ikram, M. Arfan, Nalls, Mike A., Levi, Chris, Cotlarciuc, Iona, Radmanesh, Farid, Thorleifsson, Gudmar, Hanscombe, Ken B., Langefeld, Carl, Saleheen, Danish, Rost, Natalia S.

Genetic associations with white matter hyperintensities confer risk of lacunar stroke

- Traylor, Matthew, Rutten-Jacobs, Loes C. A., Dichgans, Martin, Markus, Hugh S., Thijs, Vincent, Holliday, Elizabeth G., Levi, Chris, Bevan, Steve, Malik, Rainer, Boncoraglio, Giorgio, Sudlow, Cathie, Rothwell, Peter M.

Genome-wide association analysis of young-onset stroke identifies a locus on chromosome 10q25 near HABP2

- Cheng, Yu-Ching, Stanne, Tara M., Cole, John W., O'Connell, Jeffrey R., Danesh, John, Rasheed, Asif, Zhao, Wei, Engelter, Stefan, Grond-Ginsbach, Caspar, Kamatani, Yoichiro, Lathrop, Mark, Leys, Didier, Giese, Anne-Katrin, Levi, Christopher, Ho, Weang Kee, Traylor, Matthew, Amouyel, Philippe, Holliday, Elizabeth G., Malik, Rainer, Xu, Huichun, Kittner, Steven J.

Low-frequency and common genetic variation in ischemic stroke: the METASTROKE collaboration

- Malik, Rainer, Traylor, Matthew, Battey, Thomas W. K., Berger, Klaus, Boncoraglio, Giorgio B., Chauhan, Ganesh, Cheng, Yu-Ching, Chen, Wei-Min, Clarke, Robert, Cotlarciuc, Ioana, Debette, Stephanie, Falcone, Guido J., Pulit, Sara L., Levi, Christopher R., Bevan, Steve, Hopewell, Jemma C., Holliday, Elizabeth G., Zhao, Wei, Abrantes, Patricia, Amouyel, Philippe, Attia, John R.

Differences in common genetic predisposition to ischemic stroke by age and sex

- Traylor, Matthew, Rutten-Jacobs, Loes C. A., Dichgans, Martin, Levi, Chris, Lewis, Cathryn M., Markus, Hugh S., Holliday, Elizabeth G., Malik, Rainer, Sudlow, Cathie, Rothwell, Peter M., Maguire, Jane M., Koblar, Simon A., Bevan, Steve, Boncoraglio, Giorgio

Genetic overlap between diagnostic subtypes of ischemic stroke

- Holliday, Elizabeth G., Traylor, Matthew, Boncoraglio, Giorgio B., Clarke, Robert, Cole, John W., Fornage, Myriam, Furie, Karen L., Ikram, M. Arfan, Jannes, Jim, Kittner, Steven J., Lincz, Lisa F., Maguire, Jane M., Malik, Rainer, Oldmeadow, Christopher, Scott, Rodney J., Levi, Christopher, Attia, John, Bevan, Steve, Falcone, Guido, Hopewell, Jemma C., Cheng, Yu-Ching, Cotlarciuc, Ioana, Bis, Joshua C., Boerwinkle, Eric

No additional prognostic value of genetic information in the prediction of vascular events after cerebral ischemia of arterial origin: The PROMISe study

- Achterberg, Sefanja, Kappelle, L. Jaap, Mali, W.P.T.M., Doevendans, P.A., Farrall, Martin, Holliday, Elizabeth G., Sudlow, Cathie, Hopewell, Jemma C., Cheng, Yu-Ching, Fornage, Myriam, Ikram, M. Arfan, Malik, Rainer, De Bakker, Paul I. W., Bevan, Steve, Thorsteinsdottir, Unnur, DeStefano, Anita L., Worrall, Bradford B., Reiner, Alex P., Mitchell, Braxtin D., Clarke, Robert, Levi, Christopher, Seshadri, Sudha, Boncoraglio, Giorgio B., Traylor, Matthew, Sharma, Pankaj, Bis, Joshua C., Gretarsdottir, Solveig, Psaty, Bruce M., Rothwell, Peter M., Rosand, Jonathan, Meschia, James F., Stefansson, Kari, Dichgans, Martin, Markus, Hugh S., Algra, Ale, Van Der Graaf, Y., Grobbee, D.E., Rutten, G.E.H.M., Visseren, F.L.J., Moll, F.L.

Shared genetic basis for migraine and ischemic stroke: a genome-wide analysis of common variants

- Malik, Rainer, Freilinger, Tobias, Bis, Joshua C., Hopewell, Jemma C., Ferrari, Michel D., Rannikmae, Kristiina, Wessman, Maija, Kallela, Mikko, Kubisch, Christian, Fornage, Myriam, Meschia, James F., Lehtimäki, Terho, Winsvold, Bendik S., Sudlow, Cathie, Clarke, Robert, Chasman, Daniel I., Mitchell, Braxton D., Maguire, Jane, Kaprio, Jakko, Farrall, Martin, Raitakari, Olli T., Kurth, Tobias, Ikram, M. Arfan, Anttila, Verneri, Reiner, Alex P., Longstreth, W. T., Rothwell, Peter M., Strachan, David P., Sharma, Pankaj, Seshadri, Sudha, Quaye, Lydia, Cherkas, Lynn, Schürks, Markus, Rosand, Jonathan, Vander Heiden, Jason, Ligthart, Lannie, Boncoraglio, Giorgio B., Davey Smith, George, van Duijn, Cornelia M., Stefansson, Kari, Worrall, Bradford B., Nyholt, Dale R., Markus, Hugh S., van den Maagdenberg, Arn M. J. M., Cotsapas, Chris, Traylor, Matthew, Zwart, John A., Palotie, Aarno, Dichgans, Martin, de Vries, Boukje, Holliday, Elizabeth G., Terwindt, Gisela M., Sturm, Jonathan

A novel MMP12 locus Is associated with large artery atherosclerotic stroke using a genome-wide age-at-onset informed approach

- Traylor, Matthew, Mäkelä, Kari-Matti, Malik, Rainer, Sudlow, Cathie, Bevan, Steve, Raitoharju, Emma, Oksala, Niku, Thijs, Vincent, Lemmens, Robin, Lindgren, Arne, Slowik, Agnieszka, Kilarski, Laura L., Maguire, Jane M., Walters, Matthew, Algra, Ale, Sharma, Pankaj, Attia, John R., Boncoraglio, Giorgio B., Rothwell, Peter M., de Bakker, Paul I. W., Bis, Joshua C., Saleheen, Danish, Holliday, ELizabeth G., Kittner, Steven J., Mitchell, Braxton D., Rosand, Jonathan, Meschia, James F., Levi, Christopher, Dichgans, Martin, Lehtimäki, Terho, Lewis, Cathryn M., Markus, Hugh S., Devan, William J., Nalls, Mike A., Wiggins, Kerri L., Zhao, Wei, Cheng, Yu-Ching, Achterberg, Sefanja

Effect of genetic variants associated with plasma homocysteine levels on stroke risk

- Cotlarciuc, Iona, Malik, Rainer, Markus, Hugh S., Rosand, Jonathan, Mitchell, Braxton D., Kittner, Steven J., Meschia, James F., van Meurs, Joyce B. J., Uitterlinden, Andre G., Worrall, Bradford B., Dichgans, Martin, Sharma, Pankaj, Holliday, Elizabeth G., Ahmadi, Kourosh R., Paré, Guillaume, Psaty, Bruce M., Fornage, Myriam, Hasan, Nazeeha, Rinne, Paul E., Ikram, M. Arfan

Meta-analysis in more than 17,900 cases of ischemic stroke reveals a novel association at 12q24.12

- Kilarski, Laura L., Achterberg, Sefanja, Walters, Matthew, Worrall, Bradford B., Sale, Michele M., Algra, Ale, Kappelle, L. Jaap, Wijmenga, Cisca, Norrving, Bo, Sandling, Johanna K., Röennblom, Lars, Goris, An, Devan, William J., Franke, Andre, Sudlow, Cathie, Rothwell, Peter M., Levi, Christopher, Holliday, Elizabeth G., Fornage, Myriam, Psaty, Bruce, Gretarsdottir, Solveig, Thorsteinsdottir, Unnar, Seshadri, Sudha, Traylor, Matthew, Mitchell, Braxton D., Kittner, Steven, Clarke, Robert, Hopewell, Jemma C., Bis, Joshua C., Boncoraglio, Giorgio B., Meschia, James, Ikram, M. Arfan, Hansen, Bjorn M., Montaner, Joan, Malik, Rainer, Thorleifsson, Gudmar, Stefanson, Kari, Rosand, Jonathan, de Bakker, Paul I. W., Farrall, Martin, Dichgans, Martin, Markus, Hugh S., Bevan, Steve, Lindgren, Arne, Pare, Guillame, Sharma, Pankaj, Slowik, Agniescka, Thijs, Vincent

Multilocus genetic risk score associates with ischemic stroke in case-control and prospective cohort studies

- Malik, Rainer, Bevan, Steve, de Stefano, Anita L., Fornage, Myriam, Psaty, Bruce M., Ikram, M. Afran, Launer, Lenore J., Van Duijn, Cornelia M., Sharma, Pankaj, Mitchell, Braxton D., Rosand, Jonathan, Meschia, James F., Nalls, Michael A., Levi, Christopher, Rothwell, Peter M., Sudlow, Cathie, Markus, Hugh S., Seshadri, Sudha, Dichgans, Martin, MD Wellcome Trust Case Control Consortium 2,, Holliday, Elizabeth G., Devan, William J., Cheng, Yu-Ching, Ibrahim-Verbaas, Carla A., Verhaaren, Benjamin F. J., Bis, Joshua C., Joon, Aron Y.

Polygenic overlap between kidney function and large artery atherosclerotic stroke

- Holliday, Elizabeth G., Traylor, Matthew, Sudlow, Cathie, Rothwell, Peter M., Coresh, Josef, Hamet, Pavel, Tremblay, Johanne, Turner, Stephen T., de Andrade, Mariza, Rao, Madhumathi, Schmidt, Reinhold, Crick, Peter A., Malik, Rainer, Robino, Antonietta, Peralta, Carmen A., Jukema, J. Wouter, Mitchell, Paul, Rosas, Silvia E., Wang, Jie Jin, Scott, Rodney J., Dichgans, Martin, Mitchell, Braxton D., Kao, W. H. Linda, Bevan, Stephen, Fox, Caroline S., Levi, Christopher, Attia, John, Markus, Hugh S., Maguire, Jane, Koblar, Simon A., Sturm, Jonathan, Hankey, Graeme J., Oldmeadow, Christopher, McEvoy, Mark

Shared genetic susceptibility to ischemic stroke and coronary artery disease : a genome-wide analysis of common variants

- Dichgans, Martin, Malik, Rainer, Ódonnell, Christopher J., Fornage, Myriam, Thorsteinsdottir, Unnur, Psaty, Bruce M., Hengstenberg, Christian, Seshadri, Sudha, Erdmann, Jeanette, Bis, Joshua C., Peters, Annette, Boncoraglio, Giorgio B., König, Inke R., März, Winfred, Meschia, James F., Kathiresan, Sekar, Ikram, M. Arfan, McPherson, Ruth, Stefansson, Kari, Sudlow, Cathie, Reilly, Muredach, Thompson, John R., Sharma, Pankaj, Rosand, Jonathon, Hopewell, Jemma C., Chambers, John C., Watkins, Hugh, Rothwell, Peter M., Roberts, Robert, Markus, Hugh S., Samani, Nilesh J., Farrall, Martin, Schunkert, Heribert, Clarke, Robert, Gretarsdottir, Solveig, Thorleifsson, Gudmar, Mitchell, Branxton D., Assimes, Themistocles L., Levi, Christopher

17q25 Locus is associated with white matter hyperintensity volume in ischemic stroke, but not with lacunar stroke status

- Adib-Samii, Poneh, Rost, Natalia, Gschwendtner, Andreas, Malik, Rainer, Richie, Alexa, Gamble, Dale, Segal, Helen, Parati, Eugenio A., Ciusani, Emilio, Holliday, Elizabeth G., Maguire, Jane, Wardlaw, Joanna, Traylor, Matthew, Worrall, Bradford, Bis, Joshua, Wiggins, Kerri L., Longstreth, Will, Kittner, Steve J., Cheng, Yu-Ching, Mosley, Thomas, Falcone, Guido J., Furie, Karen L., Leiva-Salinas, Carlos, Devan, William, Lau, Benison C., Saleem Khan, Muhammed, Australian Stroke Genetics Collaborative, Wellcome Trust Case-Control Consortium-2, METASTROKE, Sharma, Pankaj, Fornage, Miriam, Mitchell, Braxton D., Psaty, Bruce M., Sudlow, Cathie, Biffi, Alessandro, Levi, Christopher, Boncoraglio, Giorgio B., Rothwell, Peter M., Meschia, James, Dichgans, Martin, Rosand, Jonathan, Markus, Hugh S., Lanfranconi, Silvia, Fitzpatrick, Kaitlin, Bevan, Steve, Kanakis, Allison, Valant, Valerie